Gallbladder Explosion

Authored by Sandi Chen, and Mario Corro Reviewed by SIUH Sono Division

85 year old female with history of HTN and hypothyroidism presents to ED for epigastric pain that started a week ago. Pain is postprandial, moderate in intensity, stabbing, continuous and radiating to the RUQ. Associated with nausea but no vomiting. Currently denies abdominal pain but complains of nausea. She denies any fever, chills, constipation or diarrhea. The following images were obtained.

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Questions:

 

1. What is seen on the above ultrasound image?

 

2. What disease processes could lead to this ultrasound finding?

 

3.  What are the ultrasound criteria for cholelithiasis? 

 

4. What are  sonographic findings in acute cholecystitis? 

 

5. What complications can arise if the above condition is not treated?

 

Answers:

  1. Gallbladder perforation (yellow arrow)

    1. Pericholecystic fluid and 

    2. True gallbladder lumen filled with stones and sludge (red arrow)

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2. Gallbladder perforation is most commonly due to occlusion of the cystic duct by gallstone and subsequent retention of contents. The associated rise in luminal pressure limits venous and lymphatic drainage, leading to vascular compromise, necrosis, and ultimately perforation. May also arise due to laparoscopic cholecystectomy.

 3. Cholelithiasis (blue arrow): highly reflective echogenic focus within gallbladder lumen, normally with posterior acoustic shadowing. Stones will also show gravity-dependent movement.

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4.Cholecystitis:   * = most sensitive

    1. Presence of ultrasonic Murphy sign*

    2. Gallstones visualized, especially if in gallbladder neck*

    3. Anterior gallbladder wall thickening >3mm

    4. Presence of pericholecystic fluid

    5. Hydrops (>5x10cm)

(None of the above signs are pathognomonic)

5.Pericholecystic abscess, cholecystoenteric or cholecystobiliary fistula formation, bile peritonitis, pancreatitis, subphrenic or hepatic abscess formation

92 Year Old Male With Difficulty Breathing

Authored by: Ahad Anjum, Brittany Choe Edited by: SIUH Ultrasound Division

92 y M hx of afib, CLL, Lymphoma pw difficulty breathing and cough. The following was found on bedside sono of the right lung. 

QUESTIONS:

1. What is seen on the above ultrasound image?

2. What disease processes could lead to this ultrasound finding? 

3.  What are the names of the ultrasound signs seen above? 

4. What is Light's Criteria? What would you expect the results to show if you were to aspirate a sample from this finding? 

ANSWERS

1. Pleural effusion with debris (red star), most likely indicative of an exudative effusion 

2.  Malignancy, pneumonia/parapneumonic effusion, lymphoma

3. Tongue Sign (white arrow) showing the lung parenchyma floating in hypo echoic fluid indicating a pleural effusion, Spine sign (black arrow) indicates a fluid filled medium above the diaphragm in which the spine is visualized on ultrasound, which is normally not seen through a regularly aerated lung 

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4. Pleural fluid protein/serum protein >0.5, Pleural fluid LDH/Serum LDH >0.6, Pleural fluid LDH > 2/3 upper limit of LDH 

Tricky Case of Pediatric Abdominal Pain..

12yo F with no significant PMH presenting with LLQ abdominal pain that began this morning. She states it is intermittent, radiates to her back, lasts an hour and worsens when she lays down. Denies fever, nausea, vomiting, dysuria, hematuria, vaginal bleeding/discharge/itching, bloody stool, or diarrhea. Last BM was 3 days ago. Menses started December 2017; occur monthly, and last 7 days. LMP was about two weeks ago. Upreg negative. Denies prior history of sexual intercourse.

ROS:

Constitutional: No weakness or fever, +chills.

Eyes/ENT: No throat pain, rhinorrhea, or otalgia.

Resp: No SOB.

Cardio: No CP.

GI: +LLQ abdominal pain. No nausea, vomiting, diarrhea, or constipation. No hematemesis. No melena or hematochezia.

GU: No dysuria, frequency, hematuria, or vaginal bleeding/discharge.

Skin: No itching or rash.

 

Vitals: T: 99.5F  BP: 118/72 HR: 125  RR: 18  SpO2: 98%

 PE

Constitutional: NAD, well appearing.

Pulm: CTAB, no wheezes/crackles/rhonchi.

CV: Tachycardic, normal S1 and S2, no m/r/g.

GI: +TTP on LLQ, BS +, soft, nondistended, no guarding/rebound.

Back: No CVA TTP bilaterally.

Neuro: A&Ox3, moving all extremities.

Questions:

1.     What US exams would you perform for this patient, and what are you concerned about/looking for? Which probe(s) and mode would you use?

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2.     Can you identify the structures in the above images?

3.     What abnormal findings, if any, can you visualize and what would be your management?

4.     What are the sequelae of this pathology if not treated?

 

Answers:

1.    FAST exam and transabdominal pelvic exam to evaluate for any free fluid, presence of normal anatomy, flow to ovaries to r/o and look for possible ovarian torsion, TOA, etc. Use the curvilinear probe in both B mode during FAST exam and color flow when looking at ovaries.

2.    A- ovarian cyst, B- bladder, C- left ovary

3.    Large left ovarian cyst. You should be concerned for an ovarian torsion with a cyst that is this size and attempt to evaluate for flow to the left ovary. Management would include prompt OBGYN consult and prepping patient for surgery.

4.    If ovarian torsion goes untreated, this can result in necrosis to the ovary secondary to loss of blood flow.

Ultrasound Liver Rounds!

Now that we have your attention - let's talk about liver ultrasound.  A topic that we do not deal with often in the ER setting, but due to all of those FAST exams and RUQ studies that we do, it's important to be able to recognize when the liver isn't normal! 

And now, onto....

The Basics of Liver Ultrasound

The liver is a large solid vascular organ that is best visualized with a curvilinear transducer with a (low) frequency between 2-5 MHz. The patient can be examined in a supine position with normal respirations.  The normal liver has a homogenous echogenic appearance.  Any heterogenous appearance should be concerning for pathology.  Here are a few non-traumatic pathologies to be aware of during your scanning.  

Cysts

  • Simple cysts are considered the most common focal liver lesion. They are anechoic with increased through transmission, and a well-defined back wall.
  • Complex cysts are identified by internal echoes, a thick wall, septations that are numerous or thick, solid elements, or calcification and are most often due to hemorrhage
  • Vascular lesions such as aneurysms, arterioportal fistulas, and portal hepatic vein fistulas can simulate cysts on gray-scale sonography but are easily distinguished with Doppler analysis

Benign Tumors

Hemangiomas:

  • The most common benign liver neoplasm found most commonly in women.. They are classified by multiple, small, blood-filled spaces are separated by fibrous septations and lined by endothelial cells that typically do not bleed or cause symptoms. Therefore, they are usually an incidental finding on ultrasound.
  • They are defined by sharp and smooth margins that may be round or slightly lobulated. 
  • Only 2% of hemangiomas enlarge on follow-up scans and they usually remain stable overtime. If the patient does not have chronic liver disease or risk of malignancy, a homogeneous hyperechoic liver lesion requires no further evaluation.
 hemangioma

hemangioma

Focal nodular hyperplasia (FNH):

  • A benign tumor of the liver that is composed of Kupffer cells, hepatocytes, and biliary structures. FNH is usually detected as an incidental mass.
  • On ultrasound, most FNHs are isoechoic to liver parenchyma
  • Unlike hepatic adenomas, they are not related to birth control pills, although birth control pills may promote their growth. They seldom bleed or cause any clinical symptoms, although pain may be encountered when the lesions are large.
  • The differential diagnosis of FNH includes fibrolamellar carcinoma, hepatic adenoma, HCC, hemangioma, and vascular metastases. 

Hepatic adenoma:

  • Adenomas are rare benign tumors that contain normal (or occasionally slightly abnormal) hepatocytes but few Kupffer cells and virtually no bile ductules. Adenomas occur most commonly in patients taking birth control pills or anabolic steroids.
  • Their propensity to bleed makes them surgical lesions despite their benign histology. They also have a low but real risk of malignant degeneration.
  • Simple, small uncomplicated adenomas tend to be homogeneous, varied and nonspecific. In most cases additional imaging is necessary to confirm the diagnosis. 

Malignant Tumors

Metastases:

  • The lungs and liver are the most frequent sites of distant metastatic disease and usually involve both lobes of the liver.
  • Liver function tests are unreliable in detecting liver metastases.
  • Metastatic lesions have a target appearance with an echogenic or isoechoic center and a hypoechoic halo while thick halos represent proliferating tumor.
  • CT and MRI are also helpful in confirming suspected diffuse metastases. In  many clinical situations when metastatic disease is suspected biopsy is required for diagnosis.

Hepatocellular carcinoma:

  • HCC is the most common primary malignancy of the liver.
  • The growth pattern of HCC is quite variable: it may be solitary, multifocal, or diffuse and infiltrating. A typical pattern of HCC is a large dominant lesion with scattered smaller satellite lesions.
  • Most HCCs are hypervascular and variable; however, this is not always evident on Doppler, particularly in deep lesions.
  • Any solid mass detected on an initial sonogram in a patient with cirrhosis should be con­sidered malignant until proved otherwise 

Middleton WD, Kurtz AB, Hertzberg BS. Ultrasound: The Requisites. 2nd ed. Philadelphia, PA: Elsevier, Inc; 2016.

 

Case 58

51 years old male with medical history of Parkinson's disease, s/p fall with injury to the chest. Pt states that he was walking in the street, when he tripped, fell and hit his chest. No LOC. Not on AC. Patient is complaining of pain in his chest, increased stiffness and  swelling over R clavicle and R arm,  difficulty breathing. Denies any palpitations, sob, cp before falling. Denies headache, n/v, other extremity pain, back pain, neck pain.

ROS
Eyes:  No visual changes, eye pain or discharge.
ENMT:  No hearing changes, pain, discharge or infections. No neck pain or stiffness.
Cardiac: Pain over R distal clavicle and midsternal.  No edema.
Respiratory:  +SOB. No cough or respiratory distress.
GI:   No nausea, vomiting, diarrhea
GU:  No dysuria, frequency or burning.
MS:  R arm and clavicle pain and swelling. No myalgia, muscle weakness, back pain.
Neuro:  No headache or weakness.  No LOC.
Skin:  No skin rash, abrasion, laceration.

PE
GCS: 15
GENERAL: in distress due to pain
HEAD:  Atraumatic, Normocephalic
EYES: EOMI, PERRL, conjunctiva and sclera clear
NECK: No Tracheal Deviation. No Mid-line tenderness C-spine. Supple. No JVD.
CHEST/LUNG: R sided chest tenderness. 5 x5 cm  hematoma, lungs clear to auscultation bilaterally;
HEART: Regular rate and rhythm; No murmurs, rubs, or gallops
ABDOMEN: Soft, Nontender, Nondistended; Bowel sounds present
EXTREMITIES:  2+ Peripheral Pulses,
NEUROLOGY: non-focal deficits

Labs, Radiology, Cardiology, and Other Results: FAST exam negative

 CXR

CXR

 CT Scan

CT Scan

QUESTIONS

  1. What is most concerning in blunt trauma to the chest as demonstrated by the images above?

  2. What tests/imaging modalities would you perform?

  3. What findings might you see on bedside echo?

  4. What do you see on this lung ultrasound?

  5. How would you manage this patient?

ANSWERS

  1. Cardiac and lung contusion. This patient has a pulmonary hematoma secondary to sternal fracture.
  2. EKG, ECHO, cardiac enzymes, CXR, and lung ultrasound.
  3. Wall motion abnormality, usually of the right ventricle. The right heart is most commonly injured due to its position closest to the anterior chest wall. 
  4. You will see B-lines in various lung fields, which in the setting of blunt force trauma would represent pulmonary contusion. You may also see hypoechoic/anechoic sharply demarcated fluid in various lung fields with a swirling pattern, strongly indicative of a hemothorax.  Other major pulmonary injuries that should definitely be considered on ultrasound would be pneumothorax, which can be identified by absence of lung sliding, otherwise known as a “barcode sign.”
  5. Observe all patients with cardiac monitoring, interval assessment of cardiac markers, SpO2 monitoring, chest tube placement as needed, and pulmonary physical therapy.